hrp0086p2-p787 | Pituitary and Neuroendocrinology P2 | ESPE2016

Giant Macroprolactinoma in a Female Adolescent – Case Report

Hreniuc Ana , Gherasim Simona , Ungureanu Maria-Christina , Preda Cristina , Vulpoi Carmen , Mogos Voichita , Rotariu Daniel , Poeata Ion , Leustean Letitia

A female patient was firstly evaluated at the age of 12 years, complaining of headaches and visual loss. Physical examination demonstrated adequate height and weight, Tanner stage P1B1. Papillary edema was confirmed by fundus examination. MRI showed a pituitary macroadenoma, 6.6×7.3×6.1 cm with compression of the optic chiasm and bilateral cavernous sinus invasion. The first prolactin value obtained was 169.164 uUI/ml (normal<210) with the other pituitary axis wi...

hrp0082p3-d3-870 | Growth (4) | ESPE2014

Primary Amenorrhea with Normal Stature: Why Not Turner Syndrome?

Hristov Ioana , Hreniuc Ana , Gherasim Simona , Ungureanu Maria-Christina , Preda Cristina , Vulpoi Carmen , Mogos Voichita , Leustean Letitia

Background: Turner syndrome is the most common sex chromosome disorder in females and occurs in about 1/2500 newborn girls worldwide. On chromosomal analysis, the various karyotypes observed are: 45,X (50%); 45,X/46,XX (20%); 46,X, i(Xq) (15%); 46,X, r(X) or 46,X, del(X) (10%); and others (5%).Objective and hypotheses: We present the case of a 17-year-old girl referred to our service for primary amenorrhea. Clinical examination: height=163 cm (62nd perce...

hrp0082p3-d2-988 | Thyroid (1) | ESPE2014

Thyrotoxicosis in Childhood and Adolescents

Hreniuc Ana , Leustean Letitia , Bodescu Ioana , Hristov Ioana , Gherasim Simona , Preda Cristina , Vulpoi Carmen , Mogos Voichita , Ungureanu Christina

Background: There are many aspects of the child thyrotoxicosis similar as in adult but there are also particular characteristics. Thyrotoxicosis is rare in childhood and in majority is about Grave’s Disease.Study Group: 61 patients with ages between 9 and 19 years that were admitted for hyperthyroidism in our department for 19 years. The diagnosis was sustained by clinical signs, hormonal profile, and ultrasound and scintigraphy exam.<p class="a...

hrp0082p3-d2-832 | Growth (1) | ESPE2014

The Impact of GH Replacement Therapy in Children Born Small-for-Gestational-Age: growth Response and Safety Profile

Chifu Irina Oana , Bodescu Ioana , Vasiliu Ioana , Idriceanu Jeanina , Fadur Alina , Hreniuc Ana , Ungureanu Maria Christina , Leustean Letitia , Mogos Voichita , Vulpoi Carmen

Background: Children born small-for-gestational-age (SGA) have a birth weight below 2,500 g at a gestational age over 37 weeks or a birth weight or length below the 3-rd percentile for gestational age. They usually recover growth during the first 6–12 months of life, but if not so, it is unlikely the recovery to happen after the age of two unless GH replacement therapy is initiated.Objective: The aim of this study was to evaluate the 1-st year growt...